self tolerances การใช้

So many thymocytes ( T cells ) die during the maturation process because there is intensive screening to make sure each thymocyte has the ability to recognize self tolerance.
In addition to the knowledge that natural killer cells are effectors of innate immunity, recent research has uncovered information on both activating and inhibitory NK cell receptors which play important function roles including self tolerance and sustaining NK cell activity.
These cells also play a fundamental role in maintaining self tolerance by suppressing the activation and expansion of self-reactive lymphocytes that may instigate autoimmunity . 9 Through their roles in immune homeostasis, it has been shown that depletion of the T reg cell population in murine models for disease lead to enhanced immune responses to a variety of infectious agents including hepatitis C virus ( HCV ) . 10 Additionally, patients with a chronic HCV infection were shown to have higher counts of T reg cells in peripheral blood when compared with successfully treated or healthy controls . 11